Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study.

ABSTRACT:

Objectives

The aim of this study was to examine whether magnesium intake is associated with coronary artery calcification (CAC) and abdominal aortic calcification (AAC).

Background

Animal and cell studies suggest that magnesium may prevent calcification within atherosclerotic plaques underlying cardiovascular disease. Little is known about the association of magnesium intake and atherosclerotic calcification in humans.

Methods

We examined cross-sectional associations of self-reported total (dietary and supplemental) magnesium intake estimated by food frequency questionnaire with CAC and AAC in participants of the Framingham Heart Study who were free of cardiovascular disease and underwent Multi-Detector Computed Tomography (MDCT) of the heart and abdomen (n = 2,695; a

SUBMITTER: Hruby A 

PROVIDER: S-EPMC3957229 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature