The impact of policy guidelines on hospital antibiotic use over a decade: a segmented time series analysis.

ABSTRACT:

Introduction

Antibiotic pressure contributes to rising antibiotic resistance. Policy guidelines encourage rational prescribing behavior, but effectiveness in containing antibiotic use needs further assessment. This study therefore assessed the patterns of antibiotic use over a decade and analyzed the impact of different modes of guideline development and dissemination on inpatient antibiotic use.

Methods

Antibiotic use was calculated monthly as defined daily doses (DDD) per 100 bed days for nine antibiotic groups and overall. This time series compared trends in antibiotic use in five adjacent time periods identified as 'Segments,' divided based on differing modes of guideline development and implementation: Segment 1--Baseline prior to antibiotic guidelines development; Segm

SUBMITTER: Chandy SJ 

PROVIDER: S-EPMC3960230 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature