Biofilm development and enhanced stress resistance of a model, mixed-species community biofilm.

ABSTRACT: Most studies of biofilm biology have taken a reductionist approach, where single-species biofilms have been extensively investigated. However, biofilms in nature mostly comprise multiple species, where interspecies interactions can shape the development, structure and function of these communities differently from biofilm populations. Hence, a reproducible mixed-species biofilm comprising Pseudomonas aeruginosa, Pseudomonas protegens and Klebsiella pneumoniae was adapted to study how interspecies interactions affect biofilm development, structure and stress responses. Each species was fluorescently tagged to determine its abundance and spatial localization within the biofilm. The mixed-species biofilm exhibited distinct structures that were not observed in comparable single-species biofilm

SUBMITTER: Lee KW 

PROVIDER: S-EPMC3960537 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature