An exploratory study of ambient air toxics exposure in pregnancy and the risk of neuroblastoma in offspring.

ABSTRACT: Little is known about the etiology of neuroblastoma, the most common cancer in infancy. In this study, we examined maternal exposure to ambient air toxics in pregnancy in relation to neuroblastoma in the child. We ascertained all cases of neuroblastoma listed in the California Cancer Registry 1990-2007 that could be linked to a California birth certificate, and controls were selected at random from California birth records. Average air toxics exposures during pregnancy were determined based upon measures from community-based air pollution monitors. The study included 75 cases and 14,602 controls who lived with 5 km of an air pollution monitor, and we additionally examined results for those living within a smaller radius around the monitor (2.5 km). Logistic regression was used to determine

SUBMITTER: Heck JE 

PROVIDER: S-EPMC3960946 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature