Identification of carboxylesterase genes implicated in temephos resistance in the dengue vector Aedes aegypti.

ABSTRACT:

Background

Thailand is currently experiencing one of its worst dengue outbreaks in decades. As in most countries where this disease is endemic, dengue control in Thailand is largely reliant on the use of insecticides targeting both immature and adult stages of the Aedes mosquito, with the organophosphate insecticide, temephos, being the insecticide of choice for attacking the mosquito larvae. Resistance to temephos was first detected in Aedes aegypti larvae in Thailand approximately 25 years ago but the mechanism responsible for this resistance has not been determined.

Principal findings

Bioassays on Ae. aegypti larvae from Thailand detected temephos resistance ratios ranging from 3.5 fold in Chiang Mai to nearly 10 fold in Nakhon Sawan (NS) province. Synergist and biochemic

SUBMITTER: Poupardin R 

PROVIDER: S-EPMC3961196 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature