Altered BOLD response during inhibitory and error processing in adolescents with anorexia nervosa.

ABSTRACT:

Background

Individuals with anorexia nervosa (AN) are often cognitively rigid and behaviorally over-controlled. We previously showed that adult females recovered from AN relative to healthy comparison females had less prefrontal activation during an inhibition task, which suggested a functional brain correlate of altered inhibitory processing in individuals recovered from AN. However, the degree to which these functional brain alterations are related to disease state and whether error processing is altered in AN individuals is unknown.

Methodology/principal findings

In the current study, ill adolescent AN females (n = 11) and matched healthy comparison adolescents (CA) with no history of an eating disorder (n = 12) performed a validated stop signal task (SST) during function

SUBMITTER: Wierenga C 

PROVIDER: S-EPMC3961291 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature