Meta-analysis: diagnostic accuracy of antinuclear antibodies, smooth muscle antibodies and antibodies to a soluble liver antigen/liver pancreas in autoimmune hepatitis.

ABSTRACT:

Background

Antinuclear antibodies (ANA), smooth muscle antibodies (SMA) and antibodies to a soluble liver antigen/liver pancreas (anti-SLA/LP) are useful markers that can help clinicians to diagnose and classify autoimmune hepatitis (AIH).

Objectives

To determine whether ANA, SMA and anti-SLA/LP help to accurately diagnose patients with AIH.

Search strategy

The PubMed, CNKI, WANFANG, and SinoMed databases were accessed to retrieve studies published in English and Chinese. Studies published up to October 2013 were reviewed.

Selection criteria

Studies on the diagnostic value of ANA, SMA or anti-SLA/LP in the diagnosis of known or suspected AIH were included.

Data collection and analysis

Two authors evaluated studies independently and rated their methodolog

SUBMITTER: Zhang WC 

PROVIDER: S-EPMC3961308 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature