Difficulty of MRI based identification of lesion age by acute infra-tentorial ischemic stroke.

ABSTRACT:

Background

Systemic thrombolysis in acute ischemic stroke is restricted to the 4.5 h time window. Many patients are excluded from this treatment because symptom onset is unknown. Magnetic resonance imaging (MRI) studies have shown that stroke patients presenting with acute supra-tentorial diffusion-weighted imaging (DWI) lesions that do not have matching lesions on fluid attenuated inversion recovery (FLAIR) are likely to be within a 4.5 hour time window. This study examines the DWI-FLAIR mismatch in infra-tentorial stroke.

Methods

This was a retrospectively conducted substudy of the "1000+" study; a prospective, single-center observational study (http://clinicaltrials.gov; NCT00715533). Fifty-six patients with infra-tentorial stroke confirmed by MRI and known symptom onset

SUBMITTER: Grosse-Dresselhaus F 

PROVIDER: S-EPMC3961416 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature