Exposure indices for the National Children's Study: application to inhalation exposures in Queens County, NY.

ABSTRACT: Characterization of environmental exposures to population subgroups within the National Children's Study (NCS), or other large-scale human environmental health studies is essential for developing a high-quality data platform for subsequent investigations. A computational formulation utilizing the tiered exposure ranking framework is presented for calculating inhalation exposure indices (EIs) for population subgroups. This formulation employs a probabilistic approach and combines information from diverse, publicly available exposure-relevant databases and information on biological mechanisms, for ranking study locations or population subgroups with respect to potential for specific end point-related environmental exposures. These EIs capture and summarize, within a set of numerical values/r

SUBMITTER: Isukapalli SS 

PROVIDER: S-EPMC3961756 | biostudies-literature | 2013 Jan-Feb

REPOSITORIES: biostudies-literature