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Performance of risk assessment instruments for predicting osteoporotic fracture risk: a systematic review.


ABSTRACT:

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We systematically reviewed the literature on the performance of osteoporosis absolute fracture risk assessment instruments. Relatively few studies have evaluated the calibration of instruments in populations separate from their development cohorts, and findings are mixed. Many studies had methodological limitations making susceptibility to bias a concern.

Introduction

The aim of this study was to systematically review the literature on the performance of osteoporosis clinical fracture risk assessment instruments for predicting absolute fracture risk, or calibration, in populations other than their derivation cohorts.

Methods

We performed a systematic review, and MEDLINE, Embase, Cochrane Library, and multiple other literature sources were searched. Inclusio

SUBMITTER: Nayak S 

PROVIDER: S-EPMC3962543 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature