Fatty liver predicts the risk for cardiovascular events in middle-aged population: a population-based cohort study.

ABSTRACT:

Objective

We investigated if the differences in liver fat content would predict the development of non-fatal and fatal atherosclerotic endpoints (coronary heart disease and stroke).

Design, setting and participants

Our study group is a population-based, randomly recruited cohort (Oulu Project Elucidating Risk of Atherosclerosis, OPERA), initiated in 1991. The cohort consisted of 988 middle-aged Finnish participants.

Intervention

Total mortality and hospital events were followed up to 2009 based on the registry of the National Institute for Health and Welfare and the National death registry.

Main outcome measure

The severity of hepatic steatosis was measured by ultrasound and divided into three groups (0-2). Cox regression analysis was used in the statistical an

SUBMITTER: Pisto P 

PROVIDER: S-EPMC3963104 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature