A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners.

ABSTRACT: We developed a simple, rapid and efficient microwave irradiation-assisted protocol that is 1- to 2-orders of magnitude faster than conventional techniques, providing an expedient access to the sialic acid congeners Neu5Ac1Me (1), Neu5Acβ1,2Me₂ (2), Neu5Ac1Me O-peracetate (3) and 4,5-oxazoline of Neu5Ac2en1Me O-peracetate (4).

SUBMITTER: Saludes JP 

PROVIDER: S-EPMC3963703 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature