MEROPS: the database of proteolytic enzymes, their substrates and inhibitors.

ABSTRACT: Peptidases, their substrates and inhibitors are of great relevance to biology, medicine and biotechnology. The MEROPS database (http://merops.sanger.ac.uk) aims to fulfill the need for an integrated source of information about these. The database has hierarchical classifications in which homologous sets of peptidases and protein inhibitors are grouped into protein species, which are grouped into families, which are in turn grouped into clans. Recent developments include the following. A community annotation project has been instigated in which acknowledged experts are invited to contribute summaries for peptidases. Software has been written to provide an Internet-based data entry form. Contributors are acknowledged on the relevant web page. A new display showing the intron/exon structures

SUBMITTER: Rawlings ND 

PROVIDER: S-EPMC3964991 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature