DbPSHP: a database of recent positive selection across human populations.

ABSTRACT: The dbPSHP database (http://jjwanglab.org/dbpshp) aims to help researchers to efficiently identify, validate and visualize putative positively selected loci in human evolution and further discover the mechanism governing these natural selections. Recent evolution of human populations at the genomic level reflects the adaptations to the living environments, including climate change and availability and stability of nutrients. Many genetic regions under positive selection have been identified, which assist us to understand how natural selection has shaped population differences. Here, we manually collect recent positive selections in different human populations, consisting of 15,472 loci from 132 publications. We further compiled a database that used 15 statistical terms of different evoluti

SUBMITTER: Li MJ 

PROVIDER: S-EPMC3965004 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature