CollecTF: a database of experimentally validated transcription factor-binding sites in Bacteria.

ABSTRACT: The influx of high-throughput data and the need for complex models to describe the interaction of prokaryotic transcription factors (TF) with their target sites pose new challenges for TF-binding site databases. CollecTF (http://collectf.umbc.edu) compiles data on experimentally validated, naturally occurring TF-binding sites across the Bacteria domain, placing a strong emphasis on the transparency of the curation process, the quality and availability of the stored data and fully customizable access to its records. CollecTF integrates multiple sources of data automatically and openly, allowing users to dynamically redefine binding motifs and their experimental support base. Data quality and currency are fostered in CollecTF by adopting a sustainable model that encourages direct author subm

SUBMITTER: Kilic S 

PROVIDER: S-EPMC3965012 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature