Changes in HbA1c level over a 12-week follow-up in patients with type 2 diabetes following a medication change.

ABSTRACT:

Background

Current guidance about the interval needed before retesting HbA1c when monitoring for glycaemic control is based on expert opinion rather than well-powered studies. The aim of our work was to explore how fast HbA1c changes after a change in glucose-lowering medication. This has implications for whether routine HbA1c testing intervals before 12 weeks could inform diabetes medication adjustments.

Methods

This 12-week cohort study recruited patients from 18 general practices in the United Kingdom with non-insulin treated diabetes who were initiating or changing dose of oral glucose-lowering medication. HbA1c was measured at baseline and 2, 4, 8 and 12 weeks after recruitment. HbA1c levels at earlier time intervals were correlated with 12-week HbA1c. A ROC curve analy

SUBMITTER: Hirst JA 

PROVIDER: S-EPMC3965408 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature