Ocular pseudoexfoliation syndrome and vascular disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

Many studies have assessed the association between ocular pseudoexfoliation syndrome (PEX) and vascular disease and produced controversial results. We performed a meta-analysis of epidemiologic studies to evaluate this relationship.

Methods

Eligible studies that reported the incidence of vascular disease among PEX and control groups were identified via computer searches and reviewing the reference lists of the key articles. The summary odds ratio (OR) and 95% confidence interval (CI) were pooled using a random-effects model. Meta-regression to assess heterogeneity by several covariates and a subgroup analysis on study design and population were performed. Publication bias was tested by Begg's funnel plot and Egger's regression test.

Results

Sixteen eligible

SUBMITTER: Wang W 

PROVIDER: S-EPMC3965457 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature