Quantitative application of the primary progressive aphasia consensus criteria.

ABSTRACT:

Objective

To determine how well the consensus criteria could classify subjects with primary progressive aphasia (PPA) using a quantitative speech and language battery that matches the test descriptions provided by the consensus criteria.

Methods

A total of 105 participants with a neurodegenerative speech and language disorder were prospectively recruited and underwent neurologic, neuropsychological, and speech and language testing and MRI in this case-control study. Twenty-one participants with apraxia of speech without aphasia served as controls. Select tests from the speech and language battery were chosen for application of consensus criteria and cutoffs were employed to determine syndromic classification. Hierarchical cluster analysis was used to examine participants who

SUBMITTER: Wicklund MR 

PROVIDER: S-EPMC3966800 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature