Serum albumin levels are associated with cardioembolic and cryptogenic ischemic strokes: Northern Manhattan Study.

ABSTRACT:

Background and purpose

Low serum albumin concentrations have been associated with increased stroke risk, but the underlying mechanisms are less well studied. We aimed to investigate the association between serum albumin levels and ischemic stroke etiologies in a large, population-based, multiethnic, prospective, cohort study.

Methods

Participants from the Northern Manhattan Study (NOMAS; n=2986; mean age, 69±10 years) free of stroke at baseline were followed for incident stroke (a median follow-up of 12 years). Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for baseline serum albumin levels and risk of ischemic stroke and ischemic stroke subtypes after adjusting for vascular risk factors.

Results

The mea

SUBMITTER: Xu WH 

PROVIDER: S-EPMC3966953 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature