Cardiovascular risk markers associated with arterial calcification in patients with chronic kidney disease Stages 3 and 4.

ABSTRACT:

Background

The contribution of pro-inflammatory markers to cardiovascular (CV) risk and vascular calcification in chronic kidney disease (CKD) remains largely to be elucidated. We investigated the association between plasma levels of several biomarkers and calcification volume in three different vascular beds in CKD Stages 3 and 4 patients.

Methods

This is a cross-sectional, exploratory study in patients with an estimated glomerular filtration rate (eGFR) ≥20 and ≤45 mL/min/1.73 m² and serum phosphorus ≥3.5 and <6.0 mg/dL enrolled in a previously published randomized, double blind, placebo-controlled single-centre trial. Ethylenediaminetetraacetic acid (EDTA) plasma samples were collected at baseline before patients received study medication and analysed for the p

SUBMITTER: Kiu Weber CI 

PROVIDER: S-EPMC3968563 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature