Clinical comparison of distal pancreatectomy with or without splenectomy: a meta-analysis.

ABSTRACT:

Objective

A distal pancreatectomy has routinely been used for removing benign/borderline malignant tumors of the body and tail of the pancreas; however, controversy exists whether or not the spleen should be saved. Therefore, we conducted this meta-analysis for comparing the clinical outcomes of patients who underwent distal pancreatectomy with or without splenectomy.

Methods

A literature research from the databases of Medline, Embase, and Cochrane library was performed to evaluate and compare the clinical outcomes between spleen-preserving distal pancreatectomy (SPDP) and distal pancreatectomy with splenectomy (DPS). Pooled odds ratio (OR) and weighted mean difference (WMD) with 95% confidence interval (95% CI) were calculated using fixed-effects or random-effects models.

SUBMITTER: He Z 

PROVIDER: S-EPMC3969315 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature