Effect of age and dialysis vintage on obesity paradox in long-term hemodialysis patients.

ABSTRACT:

Background

In contrast to the general population, higher body mass index (BMI) is associated with greater survival in patients receiving hemodialysis (HD; "obesity paradox"). We hypothesized that this paradoxical association between BMI and death may be modified by age and dialysis vintage.

Study design

Retrospective observational study using a large HD patient cohort.

Setting & participants

123,383 maintenance HD patients treated in DaVita dialysis clinics between July 1, 2001, and June 30, 2006, with follow-up through September 30, 2009.

Predictors

Age, dialysis vintage, and time-averaged BMI. Time-averaged BMI was divided into 6 subgroups; <18.5, 18.5-<23.0, 23.0-<25.0, 25.0-<30.0, 30.0-<35.0, and ≥35.0kg/m(2). BMI category of 23-<25kg/m(2) was used as the r

SUBMITTER: Vashistha T 

PROVIDER: S-EPMC3969454 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature