Resting EEG in psychosis and at-risk populations--a possible endophenotype?

ABSTRACT:

Background

Finding reliable endophenotypes for psychosis could lead to an improved understanding of aetiology, and provide useful alternative phenotypes for genetic association studies. Resting quantitative electroencephalography (QEEG) activity has been shown to be heritable and reliable over time. However, QEEG research in patients with psychosis has shown inconsistent and even contradictory findings, and studies of at-risk populations are scarce. Hence, this study aimed to investigate whether resting QEEG activity represents a candidate endophenotype for psychosis.

Method

QEEG activity at rest was compared in four frequency bands (delta, theta, alpha, and beta), between chronic patients with psychosis (N=48), first episode patients (N=46), at-risk populations ("at risk me

SUBMITTER: Ranlund S 

PROVIDER: S-EPMC3969576 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature