Changes in diversification patterns and signatures of selection during the evolution of murinae-associated hantaviruses.

ABSTRACT: In the last 50 years, hantaviruses have significantly affected public health worldwide, but the exact extent of the distribution of hantavirus diseases, species and lineages and the risk of their emergence into new geographic areas are still poorly known. In particular, the determinants of molecular evolution of hantaviruses circulating in different geographical areas or different host species are poorly documented. Yet, this understanding is essential for the establishment of more accurate scenarios of hantavirus emergence under different climatic and environmental constraints. In this study, we focused on Murinae-associated hantaviruses (mainly Seoul Dobrava and Hantaan virus) using sequences available in GenBank and conducted several complementary phylogenetic inferences. We sought for

SUBMITTER: Castel G 

PROVIDER: S-EPMC3970142 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature