Complete dosage compensation and sex-biased gene expression in the moth Manduca sexta.

ABSTRACT: Sex chromosome dosage compensation balances homogametic sex chromosome expression with autosomal expression in the heterogametic sex, leading to sex chromosome expression parity between the sexes. If compensation is incomplete, this can lead to expression imbalance and sex-biased gene expression. Recent work has uncovered an intriguing and variable pattern of dosage compensation across species that includes a lack of complete dosage compensation in ZW species compared with XY species. This has led to the hypothesis that ZW species do not require complete compensation or that complete compensation would negatively affect their fitness. To date, only one study, a study of the moth Bombyx mori, has discovered evidence for complete dosage compensation in a ZW species. We examined another moth

SUBMITTER: Smith G 

PROVIDER: S-EPMC3971586 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature