Chromoendoscopy and Advanced Imaging Technologies for Surveillance of Patients with IBD.

ABSTRACT: Inflammatory bowel disease patients with long-standing colitis have an increased risk of colorectal cancer. The high rate of interval colitis-associated cancers among patients who adhere to a nontargeted, random biopsy surveillance strategy underlies the need for improved methods of early dysplasia detection. Compelling evidence supports the efficacy of chromoendoscopy for increasing the detection rate of dysplasia; however, this technology is currently underutilized in the clinical setting. Other contrast-based technologies-including confocal laser endomicroscopy (Pentax), endocytoscopy, multiband imaging, i-scan (Pentax), and molecular-targeted techniques-show promise in the detection of dysplasia in patients with inflammatory bowel disease. The strategies currently available for identif

SUBMITTER: Barkin JA 

PROVIDER: S-EPMC3971893 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature