Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.

ABSTRACT:

Objective

To evaluate the extent to which circulating biomarker and supplements of vitamin D are associated with mortality from cardiovascular, cancer, or other conditions, under various circumstances.

Design

Systematic review and meta-analysis of observational studies and randomised controlled trials.

Data sources

Medline, Embase, Cochrane Library, and reference lists of relevant studies to August 2013; correspondance with investigators.

Study selection

Observational cohort studies and randomised controlled trials in adults, which reported associations between vitamin D (measured as circulating 25-hydroxyvitamin D concentration or vitamin D supplement given singly) and cause specific mortality outcomes.

Data extraction

Data were extracted by two indepen

SUBMITTER: Chowdhury R 

PROVIDER: S-EPMC3972416 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature