New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations.

ABSTRACT: Monodentate phosphoramidite ligands have been developed based on enantiopure 6,6'-dimethylbiphenols with axial chirality. These chiral ligands are easy to prepare and flexible for modifications. The fine-tuning capability of these ligands plays a significant role in achieving high enantioselectivity in the asymmetric hydroformylation of allyl cyanide and the conjugate addition of diethylzinc to cycloalkenones.

SUBMITTER: Hua Z 

PROVIDER: S-EPMC397395 | biostudies-literature | 2004 Apr

REPOSITORIES: biostudies-literature