An atypical winter outbreak of hand, foot, and mouth disease associated with human enterovirus 71, 2010.

ABSTRACT:

Background

To analyze the epidemiological characteristics and pathogenic molecular characteristics of an hand, foot, and mouth disease (HFMD) outbreak caused by enterovirus 71 in Linyi City, Shandong Province, China during November 30 to December 28, 2010.

Methods

One hundred and seventy three stool specimens and 40 throat samples were collected from 173 hospitalized cases. Epidemiologic and clinical investigations, laboratory testing, and genetic analyses were performed to identify the causal pathogen of the outbreak.

Results

Among the 173 cases reported in December 2010, the male-female ratio was 1.88: 1; 23 cases (13.3%) were severe. The majority of patients were children aged < 5 years (95.4%). Some patients developed respiratory symptoms including runny nose (38.

SUBMITTER: Liu N 

PROVIDER: S-EPMC3974002 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature