Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial.

ABSTRACT:

Background

To evaluate if an opiate sparing multimodal regimen of dexamethasone, gabapentin, ibuprofen and paracetamol had better analgesic effect, less side effects and was safe compared to a traditional morphine and paracetamol regimen after cardiac surgery.

Methods

Open-label, prospective randomized controlled trial. 180 patients undergoing cardiac procedures through median sternotomy, were included in the period march 2007-August 2009. 151 patients were available for analysis. Pain was assessed with the 11-numeric rating scale (11-NRS).

Results

Patients in the multimodal group demonstrated significantly lower average pain scores from the day of surgery throughout the third postoperative day. Extensive nausea and vomiting, was found in no patient in the multimodal

SUBMITTER: Rafiq S 

PROVIDER: S-EPMC3975463 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature