Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.

ABSTRACT: The 2005 National Institutes of Health (NIH) consensus criteria for chronic GVHD have set standards for reporting. Many questions, however, have arisen regarding their implementation and utilization. To identify perceived areas of controversy, we conducted an international survey on diagnosis and scoring of chronic GVHD. Agreement was observed for 50-83% of the 72 questions in 7 topic areas. There was agreement on the need for modifying criteria in six situations: two or more distinctive manifestations should be enough to diagnose chronic GVHD; symptoms that are not due to chronic GVHD should be scored differently; active disease and fixed deficits should be distinguished; a minimum threshold body surface area of hidebound skin involvement should be required for a skin score of 3; asymptom

SUBMITTER: Inamoto Y 

PROVIDER: S-EPMC3975688 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature