Diagnostic accuracy of copeptin sensitivity and specificity in patients with suspected non-ST-elevation myocardial infarction with troponin I below the 99th centile at presentation.

ABSTRACT:

Objective

To determine whether copeptin-us can rule out diagnosis of non-ST-segment elevation myocardial infarction (NSTEMI) without prolonged monitoring and serial blood sampling in patients with high-sensitive cardiac troponin I (hs-cTnI) below the 99th centile at presentation to the emergency department (ED) [corrected].

Design

Prospective, non-randomised, individual blinded diagnostic accuracy study.

Setting

Two EDs of a rural region of France.

Participants

Patients with chest pain suspected of NSTEMI with onset within the last 12 h were considered for enrollment.

Interventions

Serial clinical, electrographical and biochemical investigations were performed at admission and after 2, 4, 6 and 12 h. Hs-cTnI was measured using an assay with Dimension VIS

SUBMITTER: Duchenne J 

PROVIDER: S-EPMC3975746 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature