Opioid utilization and opioid-related adverse events in nonsurgical patients in US hospitals.

ABSTRACT:

Background

Recent studies in the outpatient setting have demonstrated high rates of opioid prescribing and overdose-related deaths. Prescribing practices in hospitalized patients are unexamined.

Objective

To investigate patterns and predictors of opioid utilization in nonsurgical admissions to US hospitals, variation in use, and the association between hospital-level use and rates of severe opioid-related adverse events.

Design, setting, and patients

Adult nonsurgical admissions to 286 US hospitals.

Measurements

Opioid exposure and severe opioid-related adverse events during hospitalization, defined using hospital charges and International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes.

Results

Of 1.14 million admissio

SUBMITTER: Herzig SJ 

PROVIDER: S-EPMC3976956 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature