A new diagnostic test for endometrial cancer?: Cytology analysis of sonohysterography distention media.

ABSTRACT:

Objective

During saline-infused sonohysterography (SIS), the distension fluid is typically discarded. If cytology analysis could identify those patients with endometrial cancer, many women would be spared from further procedures.

Methods

Thirty consecutive patients with clinical stage I or II endometrial adenocarcinoma were prospectively recruited preoperatively. Saline-infused sonohysterography was performed by instilling 5 mL of saline, withdrawing and sending for analysis. Saline was reinfused until complete SIS images were obtained and sent separately for cytology.

Results

Of the 30 women enrolled, SIS was technically successful in 29. Demographics included mean age (60.5 ± 6.99 years), body mass index (35.55 ± 8.18 kg/m), endometrioid histology (76%), and grade (

SUBMITTER: Guralp O 

PROVIDER: S-EPMC3976997 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature