Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies.

ABSTRACT:

Objectives

To review, summarise, and compare the evidence for effectiveness of screening sigmoidoscopy and screening colonoscopy in the prevention of colorectal cancer occurrence and deaths.

Design

Systematic review and meta-analysis of randomised controlled trials and observational studies.

Data sources

PubMed, Embase, and Web of Science. Two investigators independently extracted characteristics and results of identified studies and performed standardised quality ratings.

Eligibility criteria

Randomised controlled trials and observational studies in English on the impact of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality in the general population at average risk.

Results

For screening sigmoidoscopy, four ra

SUBMITTER: Brenner H 

PROVIDER: S-EPMC3980789 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature