Extent of lymphadenectomy and perioperative therapies: two open issues in gastric cancer.

ABSTRACT: Gastric cancer is one of the leading causes of death for cancer worldwide, although geographical variations in incidence exist. Over the last decades, its incidence and mortality have gradually decreased in Western countries, while these have increased, or remained stable, in the other world regions. Gastric cancer is often diagnosed at an advanced stage, with the only notable exception of Japan, where nationwide screening programs are enforced, due to local high incidence. Curative- intent surgery (i.e., gastrectomy, total or partial, and lymphadenectomy) remains the cornerstone of treatment of gastric cancer. Much has been debated about the extent of lymph node dissection and, although it is a valuable contribution to staging and cure, operative treatment only represents one aspect of ov

SUBMITTER: Giuliani A 

PROVIDER: S-EPMC3983445 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature