Circulating irisin levels are not affected by coffee intake: a randomized controlled trial.

ABSTRACT:

Unlabelled

Irisin, secreted by skeletal muscle and possibly fat, is hypothesized to play an important role in modulating energy expenditure, obesity and metabolism. Coffee consumption also increases energy expenditure and leads to positive metabolic effects, but whether these effects are mediated by irisin remains unknown. The objective of this study was to determine the association between baseline irisin levels and the metabolic profile in humans and to investigate whether consumption of caffeinated coffee alters irisin levels. To this end, a secondary analysis was performed investigating irisin levels at baseline and after eight weeks in 32 healthy, overweight coffee drinkers who were randomized to consumption of 5 cups per day of instant caffeinated coffee, decaffeinated coffee

SUBMITTER: Peter PR 

PROVIDER: S-EPMC3984159 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature