Therapy optimization in multiple sclerosis: a prospective observational study of therapy compliance and outcomes.

ABSTRACT:

Background

Data sources for MS research are numerous but rarely provide an objective measure of drug therapy compliance coupled with patient-reported health outcomes. The objective of this paper is to describe the methods and baseline characteristics of the Therapy Optimization in MS (TOP MS) study designed to investigate the relationship between disease-modifying therapy compliance and health outcomes.

Methods

TOP MS was designed as a prospective, observational, nationwide patient-focused study using an internet portal for data entry. The protocol was reviewed and approved by Sterling IRB. The study was registered with ClinicalTrials.gov. It captured structured survey data monthly from MS patients recruited by specialty pharmacies. Data collection included the clinical char

SUBMITTER: Coyle PK 

PROVIDER: S-EPMC3984676 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature