Whole-genome sequencing of Berkshire (European native pig) provides insights into its origin and domestication.

ABSTRACT: Domesticated organisms have experienced strong selective pressures directed at genes or genomic regions controlling traits of biological, agricultural or medical importance. The genome of native and domesticated pigs provide a unique opportunity for tracing the history of domestication and identifying signatures of artificial selection. Here we used whole-genome sequencing to explore the genetic relationships among the European native pig Berkshire and breeds that are distributed worldwide, and to identify genomic footprints left by selection during the domestication of Berkshire. Numerous nonsynonymous SNPs-containing genes fall into olfactory-related categories, which are part of a rapidly evolving superfamily in the mammalian genome. Phylogenetic analyses revealed a deep phylogenetic sp

SUBMITTER: Li M 

PROVIDER: S-EPMC3985078 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature