A phylogenomics approach for selecting robust sets of phylogenetic markers.

ABSTRACT: Reconstructing the evolutionary relationships of species is a major goal in biology. Despite the increasing number of completely sequenced genomes, a large number of phylogenetic projects rely on targeted sequencing and analysis of a relatively small sample of marker genes. The selection of these phylogenetic markers should ideally be based on accurate predictions of their combined, rather than individual, potential to accurately resolve the phylogeny of interest. Here we present and validate a new phylogenomics strategy to efficiently select a minimal set of stable markers able to reconstruct the underlying species phylogeny. In contrast to previous approaches, our methodology does not only rely on the ability of individual genes to reconstruct a known phylogeny, but it also explores the

SUBMITTER: Capella-Gutierrez S 

PROVIDER: S-EPMC3985644 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature