An agent-based model of the response to angioplasty and bare-metal stent deployment in an atherosclerotic blood vessel.

ABSTRACT:

Purpose

While animal models are widely used to investigate the development of restenosis in blood vessels following an intervention, computational models offer another means for investigating this phenomenon. A computational model of the response of a treated vessel would allow investigators to assess the effects of altering certain vessel- and stent-related variables. The authors aimed to develop a novel computational model of restenosis development following an angioplasty and bare-metal stent implantation in an atherosclerotic vessel using agent-based modeling techniques. The presented model is intended to demonstrate the body's response to the intervention and to explore how different vessel geometries or stent arrangements may affect restenosis development.

Methods

The

SUBMITTER: Curtin AE 

PROVIDER: S-EPMC3986389 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature