AmrZ is a global transcriptional regulator implicated in iron uptake and environmental adaption in P. fluorescens F113.

ABSTRACT:

Background

AmrZ, a RHH transcriptional regulator, regulates motility and alginate production in pseudomonads. Expression of amrZ depends on the environmental stress sigma factor AlgU. amrZ and algU mutants have been shown to be impaired in environmental fitness in different pseudomonads with different lifestyles. Considering the importance of AmrZ for the ecological fitness of pseudomonads and taking advantage of the full sequencing and annotation of the Pseudomonas fluorescens F113 genome, we have carried out a ChIP-seq analysis from a pool of eight independent ChIP assays in order to determine the AmrZ binding sites and its implication in the regulation of genes involved in environmental adaption.

Results

154 enriched regions (AmrZ binding sites) were detected in this anal

SUBMITTER: Martinez-Granero F 

PROVIDER: S-EPMC3986905 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature