Predictors of mortality among bacteremic patients with septic shock receiving appropriate antimicrobial therapy.

ABSTRACT:

Background

Factors capable of impacting hospital mortality in patients with septic shock remain uncertain. Our objective was to identify predictors of hospital mortality among patients who received appropriate antimicrobial therapy for bacteremic septic shock after accounting for severity of illness, resuscitation status, and processes of care.

Methods

We conducted a secondary subgroup analysis of a prospective severe sepsis cohort study. Patients with septic shock and positive blood cultures who received appropriate antimicrobial therapy were included. Univariable analyses were used to identify differences between hospital survivors and non-survivors, and a multivariable logistic regression model revealed independent determinants of hospital mortality.

Results

From J

SUBMITTER: Leedahl DD 

PROVIDER: S-EPMC3987695 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature