Case-control study of factors that trigger inflammatory bowel disease flares.

ABSTRACT:

Aim

To explore the association between inflammatory bowel diseases (IBD) flares and potential triggers.

Methods

Patients evaluated for an acute flare of IBD by a gastroenterologist at the Dallas VA Medical Center were invited to participate, as were a control group of patients with IBD in remission. Patients were systematically queried about nonsteroidal anti-inflammatory drug use, antibiotic use, stressful life events, cigarette smoking, medication adherence, infections, and travel in the preceding 3 mo. Disease activity scores were calculated for each patient at the time of enrollment and each patient's chart was reviewed. Multivariate regression analysis was performed.

Results

A total of 134 patients with IBD (63 with Crohn's disease, 70 with ulcerative colitis, an

SUBMITTER: Feagins LA 

PROVIDER: S-EPMC3989967 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature