Safety and Efficacy of Micro-focused Ultrasound Plus Visualization for the Treatment of Axillary Hyperhidrosis.

ABSTRACT:

Objectives

To evaluate the safety, efficacy, and durability of treating axillary hyperhidrosis with high-intensity micro-focused ultrasound plus visualization.

Design

Two randomized double-blind, sham-controlled pilot studies.

Measurements

For Study 1, the primary endpoint was response defined as ≥50-percent reduction in baseline sweat production as measured gravimetrically. For Study 2, the primary endpoint was response defined as a reduction of Hyperhidrosis Disease Severity Scale scores from 3 or 4 to 1 or 2. Secondary endpoints included changes in gravimetric and starch-iodine testing and patient satisfaction.

Results

In Study 1, ≥50 percent of patients achieved a positive treatment response. In Study 2, the response rate at post-treatment Day 60 for micro-

SUBMITTER: Nestor MS 

PROVIDER: S-EPMC3990536 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature