Polarity-specific effects of motor transcranial direct current stimulation on fMRI resting state networks.

ABSTRACT: Transcranial direct current stimulation (tDCS) has been used to modify motor performance in healthy and patient populations. However, our understanding of the large-scale neuroplastic changes that support such behavioural effects is limited. Here, we used both seed-based and independent component analyses (ICA) approaches to probe tDCS-induced modifications in resting state activity with the aim of establishing the effects of tDCS applied to the primary motor cortex (M1) on both motor and non-motor networks within the brain. Subjects participated in three separate sessions, during which resting fMRI scans were acquired before and after 10min of 1mA anodal, cathodal, or sham tDCS. Cathodal tDCS increased the inter-hemispheric coherence of resting fMRI signal between the left and right suppl

SUBMITTER: Amadi U 

PROVIDER: S-EPMC3991849 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature