Polyphenols from olive mill waste affect biofilm formation and motility in Escherichia coli K-12.

ABSTRACT: Olive mill wastes are sources of phenolic compounds with a wide array of biological activities, including antimicrobial effects. A potential option for bioremediation to overcome ecological problems is the reutilization of these natural compounds in food production. The aim of this work was to gain a better understanding of the antimicrobial mode of action of a phenols extract from olive vegetation water (PEOVW) at molecular level by studying Escherichia coli as a model microorganism. Genome-wide transcriptional analysis was performed on E. coli K-12 exposed to PEOVW. The repression of genes for flagellar synthesis and the involvement of genes linked to biofilm formation and stress response were observed. Sub-inhibitory concentrations of PEOVW significantly decreased biofilm formation, swa

SUBMITTER: Carraro L 

PROVIDER: S-EPMC3992022 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature