A preoperative nomogram for the prediction of ipsilateral central compartment lymph node metastases in papillary thyroid cancer.

ABSTRACT:

Background

Central compartment lymph node metastases in papillary thyroid carcinoma (PTC) are difficult to detect preoperatively, and the role of routine or prophylactic central compartment lymph node dissection (CLND) in managing PTC remains controversial. The aim of this project was to create a nomogram able to predict the occurrence of central compartment lymph node metastasis using readily available preoperative clinical characteristics.

Methods

Records from patients undergoing total thyroidectomy and lymph node dissection for PTC in the period 1968-2012 were analyzed. Nodal status was based on results of serial hematoxylin and eosin (H&E) examination. Age, sex, tumor size, tumor site, and multifocality were included in a multivariable logistic regression model to predic

SUBMITTER: Thompson AM 

PROVIDER: S-EPMC3993080 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature