Demonstration of plasmid-mediated drug resistance in Mycobacterium abscessus.

ABSTRACT: Plasmid-mediated kanamycin resistance was detected in a strain of Mycobacterium abscessus subsp. bolletii responsible for a nationwide epidemic of surgical infections in Brazil. The plasmid did not influence susceptibility to tobramycin, streptomycin, trimethoprim-sulfamethoxazole, clarithromycin, or ciprofloxacin. Plasmid-mediated drug resistance has not been described so far in mycobacteria.

SUBMITTER: Matsumoto CK 

PROVIDER: S-EPMC3993635 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature