Estimate of venous thromboembolism and related-deaths attributable to the use of combined oral contraceptives in France.

ABSTRACT:

Purpose

To estimate the number of venous thromboembolic events and related-premature mortality (including immediate in-hospital lethality) attributable to the use of combined oral contraceptives in women aged 15 to 49 years-old between 2000 and 2011 in France.

Methods

French data on sales of combined oral contraceptives and on contraception behaviours from two national surveys conducted in 2000 and 2010 were combined to estimate the number of exposed women according to contraceptives generation and age. Absolute risk of first time venous thromboembolism in non-users of hormonal contraception and increased risk of thromboembolism in users vs. non-users of hormonal contraception were estimated on the basis of literature data. Finally, immediate in-hospital lethality due to pul

SUBMITTER: Tricotel A 

PROVIDER: S-EPMC3994005 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature